46 out of 150 cities on the 'Best Places to Live' list from U.S. Winston-Salem is also home to six colleges and institutions, most notably Wake Forest University, Winston-Salem State University, and the University of North Carolina School of the Arts, which ranks as one of the best arts schools in America. Many natives of the city and North Carolina refer to the city as 'Winston' in informal speech. Winston-Salem is called the 'Twin City' for its dual heritage, and 'the Camel City' is a reference to the city's historic involvement in the tobacco industry related to locally based R. The metro area covers over 2,000 square miles and spans the five counties of Forsyth, Davidson, Stokes, Davie, and Yadkin. The population of the Winston-Salem metropolitan area in 2020 was 679,948. In 2003, the Greensboro–Winston-Salem– High Point Metropolitan Statistical Area was redefined by the OMB and separated into the two major metropolitan areas of Winston-Salem and Greensboro-High Point. Winston-Salem is home to the tallest office building in the region, 100 North Main Street, formerly known as the Wachovia Building and now known locally as the Wells Fargo Center. With a metropolitan population of 675,966, it is the 4th largest metropolitan area in North Carolina. In the 2020 census, the population was 249,545, making it the second-largest municipality in the Piedmont Triad region, the 5th most populous city in North Carolina, the third-largest urban area in North Carolina, and the 90th most populous city in the United States.

Winston-Salem is a city in and the county seat of Forsyth County, North Carolina, United States.

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